(R)-1-(Isopropylamino)-3-[4-(2-isopropoxyethoxymethyl)phenoxy]-2-propanol
1-[isopropylamino]-3-[isopropoxyethoxymethylphenoxy]-2-propanol
CAS: 66722-44-9
Molecular Formula: C18H31NO4
(R)-1-(Isopropylamino)-3-[4-(2-isopropoxyethoxymethyl)phenoxy]-2-propanol - Names and Identifiers
(R)-1-(Isopropylamino)-3-[4-(2-isopropoxyethoxymethyl)phenoxy]-2-propanol - Physico-chemical Properties
| Molecular Formula | C18H31NO4 |
| Molar Mass | 325.44 |
| Density | 1.033±0.06 g/cm3(Predicted) |
| Melting Point | 100 °C |
| Boling Point | 445.0±45.0 °C(Predicted) |
| Water Solubility | 5.5ug/L(100 ºC) |
| Solubility | Chloroform (Sparingly), Methanol (Slightly) |
| Appearance | neat |
| Color | Yellow |
| pKa | pKa 9.57(H2O(extrap) t=25±1 Iunde?ned Aratmosphere) (Uncertain) |
| Storage Condition | -20°C Freezer, Under Inert Atmosphere |
| Use | For the treatment of cardiovascular and cerebrovascular diseases |
(R)-1-(Isopropylamino)-3-[4-(2-isopropoxyethoxymethyl)phenoxy]-2-propanol - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 1 |
| RTECS | UB8380000 |
| Hazard Class | IRRITANT |
(R)-1-(Isopropylamino)-3-[4-(2-isopropoxyethoxymethyl)phenoxy]-2-propanol - Nature
Open Data Verified Data
Bisoprolol hemifumarate Crystal, melting point 100 °c. Soluble in ethanol.
Last Update：2024-01-02 23:10:35
(R)-1-(Isopropylamino)-3-[4-(2-isopropoxyethoxymethyl)phenoxy]-2-propanol - Preparation Method
Open Data Verified Data
4-[(2-isopropoxyethoxy) methyl] phenol is reacted with epichlorohydrin, and the resulting epoxide is reacted with isopropylamine to obtain Bisoprolol.
Last Update：2022-01-01 09:10:08
(R)-1-(Isopropylamino)-3-[4-(2-isopropoxyethoxymethyl)phenoxy]-2-propanol - Use
Open Data Verified Data
developed by E.Merock, Germany, launched in 1986. It is a β1-blocker with high affinity and selectivity for cardiac-receptors, and its β1-selectivity is higher than that of cardiac-selective β1-blockers such as Atenolol and metoprolol. No cell membrane stabilizing effect in the therapeutic dose range. It is used for hypertension and coronary heart disease, and is relatively safe for hypertensive patients with asthma.
Last Update：2022-01-01 09:10:08
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Product Name: Bisoprolol Monomer Visit Supplier Webpage Request for quotationCAS: 66722-44-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
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